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. 2016 Dec 20;8(6):9267–9279. doi: 10.18632/oncotarget.14035

Figure 1. Sirt1 was reduced along with increased ER stress in brown adipose tissue of obese mice.

Figure 1

(A) Body weight of mice fed on high fat diet (HFD) and chow diet (n = 6); (B) Food intake of mice fed on HFD and chow diet (n = 6); (C) The mRNA expression of Sirt1, Sirt2, Sirt3 in interscapular brown adipose tissue (iBAT) and inguinal white adipose tissue (iWAT) of mice fed on HFD or chow diet (n = 6); (D) The mRNA expression of UCP1, PRDM16 and Cidea in iBAT of mice fed on HFD or chow diet (n = 6); (E) The mRNA expression of GRP78, Chop, ATF4, ATF6 and Caspase3 in iBAT of mice fed on HFD or chow diet (n = 6). Values are means ± SEM, *p < 0.05 compared with the control group.