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. 2016 Dec 21;8(6):9354–9365. doi: 10.18632/oncotarget.14069

Figure 1. IHC and HE staining characteristics of MLH1, MSH2, PD-1, PD-L1 and stroma density.

Figure 1

(A) High MLH1 expression was observed in the nucleus. (B) Low MLH1 expression. (C) High MSH2 expression was observed in the nucleus. (D) Low MSH2 expression. (E) PD-1 was located on cell menbranes of TILs, clusters of PD-1+ TILs were observed. (F) Sporadic PD-1+ TILs were observed. (G) High PD-1 expression was observed on cell menbranes of cancer cells. (H) Low PD-L1 expression. (I) H&E staining showed PC tissue with dense stroma. (J) H&E staining showed PC tissue with moderate stroma. Magnification, x200 (A–H); Magnification, x100 (I, J).