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. 2016 Dec 21;8(6):9354–9365. doi: 10.18632/oncotarget.14069

Table 2. Correlation between the clinicopathologic characteristics and MLH1/MSH2 expression.

MLH1 MSH2
Low High P value Low High P value
Age
 < 60 years 10 (34.5%) 19 (65.5%) 0.820a 9 (31.0%) 20 (69.0%) 0.323a
 ≥ 60 years 24 (36.9%) 41 (63.1%) 14 (21.5%) 51 (78.5%)
Gender
 Male 24 (38.1%) 39 (61.9%) 0.580a 14 (22.2%) 49 (77.8%) 0.470a
 Female 10 (32.3%) 21 (67.7%) 9 (29.0%) 22 (71.0%)
Tumor site
 Head, neck 16 (33.3%) 32 (66.7%) 0.505a 14 (29.2%) 34 (70.8%) 0.306a
 Body, tail 18 (40.0%) 27 (60.0%) 9 (20.0%) 36 (80.0%)
T stage
 T1+T2 5 (25.0%) 15 (75.0%) 0.226a 3 (15.0%) 17 (85.0%) 0.382a
 T3+T4 29 (39.7%) 44 (60.3%) 20 (27.4%) 53 (72.6%)
N stage
 N0 (negative) 14 (35.0%) 26 (65.0%) 0.786a 7 (17.5%) 33 (82.5%) 0.160a
 N1 (positive) 20 (37.7%) 33 (62.3%) 16 (30.2%) 37 (69.8%)
Metastasis
 M0 (absent) 33 (37.1%) 56 (62.9%) 1.000b 21 (23.6%) 68 (76.4%) 0.255b
 M1 (present) 1 (25.0%) 3 (75.0%) 2 (50.0%) 2 (50.0%)
Differentiation
 G1 and G2 19 (31.1%) 42 (68.9%) 0.168a 11 (18.0%) 50 (82.0%) 0.094a
 G3 15 (45.5%) 18 (54.5%) 11 (33.3%) 22 (66.7%)
Vascular invasion
 No 32 (39.5%) 49 (60.5%) 0.199a 21 (25.9%) 60 (74.1%) 0.724a
 Yes 2 (16.7%) 10 (83.3%) 2 (16.7%) 10 (83.3%)
Nervous invasion
 No 11 (39.3%) 17 (60.7%) 0.720a 5 (17.9%) 23 (82.1%) 0.313a
 Yes 23 (35.4%) 42 (64.6%) 18 (27.7%) 47 (72.3%)

aChi-square test; bFisher's exact test