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. 2016 Dec 22;8(6):9399–9409. doi: 10.18632/oncotarget.14090

Figure 2. CaCl2 reversed resveratrol's effect, while EGTA and ryanodine potentiated the antinociceptive effects of resveratrol.

Figure 2

CaCl2 (25, 50, 100 and 200 nmol, i.c.v), EGTA (5, 15 and 30 nmol, i.c.v) and ryanodine (0.25, 0.5, 1 and 2 nmol, i.c.v) were administered 30 min before resveratrol treatment. Mean ± SEM, n = 8. *p < 0.05 and **p < 0.01, compared to the vehicle + resveratrol (10 or 20 mg/kg) group.

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