Table 1. Univariate and multivariate Cox regression analysis of the 18-mRNA and one-lncRNA module in LC patients.

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI of HR	P-value	HR	95% CI of HR	P-value
Training dataset
18-mRNA and one-lncRNA module	2.72	1.68-4.39	<0.0001	2.83	1.65-4.84	<0.0001
Grade	1.27	0.590-2.71	0.546	0.837	0.319-2.20	0.719
Age	0.992	0.938-1.05	0.793	1.02	0.941-1.10	0.666
Test dataset
18-mRNA and one-lncRNA module	3.15	1.12-8.85	2.93e-2	3.34	1.18-9.43	2.30e-2
Grade	0.824	0.426-1.59	0.565	0.731	0.385-1.39	0.336
Age	1.04	1.00-1.09	5.20e-2	1.04	0.997-1.09	6.60e-2
Entire dataset
18-mRNA and one-lncRNA module	1.20	1.09-1.33	<0.0001	1.20	1.08-1.33	<0.0001
Grade	1.00	0.608-1.65	0.999	0.902	0.541-1.51	0.694
Age	1.02	0.989-1.06	0.192	1.02	0.985-1.06	0.249