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. 2016 Dec 24;8(6):9572–9586. doi: 10.18632/oncotarget.14161

Figure 5. Kaplan-Meier and ROC curves of biochemical recurrence.

Figure 5

A. The main cohort shows clear separation in biochemical recurrence free survival between the low, intermediate and high NCWP-EMT signature groups. B. A validation cohort (GSE21034) shows the same pattern, although not a significant separation. C. A similar pattern was also shown for the patient of the main cohort with a post-operative Gleason score of 7. D. The ROC curves of biochemical recurrence after 5 years show the same AUC of post-operative Gleason score and NCWP-EMT, but an increased AUC when combined. Δ Continuous NCWP-EMT signature score, * continuous post-operative Gleason score. Abbreviations: BCR - biochemical recurrence, RP – radical prostatectomy, ROC – Receiver operating characteristic, and AUC – area under the curve.