Table 3. Univariate and multivariate Cox proportional hazards analyses of biochemical recurrence.

	Univariate		Multivariate – All variables(AIC = 60.15)
Variables	Hazard ratio (95% CI)	P-values	Hazard ratio (95% CI)	P-values
Post-operative Gleason score(≤7Δ and ≥8)	7.66(2.20-26.62)	0.001*	19.46(2.67-142.9)	0.003*
Pathological T-stage(≤T2cΔ and ≥T3a)	6.88(2.06-23.01)	0.002*	8.27(0.89-77.15)	0.064
Pre-operative PSA(<10Δ and ≥10)	2.17(0.69-7.13)	0.204	2.89(0.72-11.67)	0.14
NCWP-EMTContinuous score/100 (-4.4–5.4)	1.37(1.08-1.73)	0.009*	Low GS1.61(1.06-2.44)	Low GS0.028*
			High GS0.59(0.35-0.99)	High GS0.044*
NCWP-EMT andPost-operative Gleason score (≤7Δ and ≥8)(interaction term)	-	-	0.37(0.18-0.74)	0.005*

^Δ Indicates the category used as a reference in each analysis.

* Indicates significant p-value.

Low GS – Hazard ratio/p-value for patients with post-operative Gleason score ≤7

High GS – Hazard ratio/p-value for patients with post-operative Gleason score ≥8