Figure 12. Telomerase-driven cancer stem-like cells: Are they also involved in tumor dormancy?

Here, we observed that the hTERT-high cell population could be further divided into i) proliferating and ii) non-proliferating sub-populations, using EdU incorporation to monitor DNA-synthesis (S-phase). We speculate that the quiescent hTERT-high CSCs could be involved in tumor dormancy. See the Discussion section for further elaboration on this point.