Table 1. Proteomics: Key Molecules Up-regulated in hTERT-GFP(+) A549 Lung Cancer Cells Isolated by FACS.

Symbol	Description	Fold-Upregulation(GPF(+)/GFP(-))
Mitochondrial-related proteins
ALDH2	Aldehyde dehydrogenase, mitochondrial	Infinity
AK2	Adenylate kinase 2, mitochondrial	27.20
ATP5B	ATP synthase subunit beta	9.48
IMMT	Mitochondrial inner membrane protein	9.20
MRPL49	Mitochondrial ribosomal protein L49	7.12
PRKDC	DNA-dependent protein kinase catalytic subunit	6.26
HSPA9	Heat shock 70 kDa protein 9	6.00
MT-CO2	Cytochrome c oxidase subunit 2, mt-DNA encoded	3.99
NDUFS2	NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial	3.76
ETFA	Electron transfer flavoprotein subunit alpha, mitochondrial	2.83
SLC25A10	Mitochondrial dicarboxylate carrier	2.39
ATP5O	ATP synthase subunit O, mitochondrial	2.36
VDAC1	Voltage-dependent anion-selective channel protein 1	2.27
SLC25A5	Mitochondrial Carrier; Adenine Nucleotide Translocator, Member 5	1.99
HSPD1	60 kDa heat shock protein, mitochondrial	1.98
Glycolysis and PPP
LDHB	L-lactate dehydrogenase B	50.93
G6PD	Glucose-6-phosphate 1-dehydrogenase	17.85
TPI1	Triosephosphate isomerase 1	17.41
PGK1	Phosphoglycerate kinase 1	9.49
ALDOA	Fructose-bisphosphate aldolase	3.32
PGD	6-phosphogluconate dehydrogenase, decarboxylating	3.21
PKM2	Pyruvate kinase	1.93
Glycogen-related
PYGB	Glycogen phosphorylase, brain form	2.23

Proteomic analysis of hTERT-GFP A549 cells. Data are derived from the analysis of FACS sorted cell populations. The fold-increase of certain key molecules in GFP(+) cells is shown, relative to GFP(-) cells. Note that several protein targets related to mitochondria, glycolysis, and glycogenolysis are increased in GFP(+) cells.