Table 1. Results from univariate analysis for organ preservation protocol response and microRNA expression (qPCR) for the ‘validation set’.

	Overall response after chemoradiation (CRT)
	Responders (CR)n (%)	Non-responders (PR+SD+TP)n (%)	p-value
miR-21
Low expression	14 (60.9)	7 (29.2)	0.029
High expression	9 (39.1)	17 (70.8)
miR-494
Low expression	10 (43.5)	9 (37.5)	0.676
High expression	13 (56.5)	15 (62.5)
miR-720
Low expression	12 (52.2)	10 (41.7)	0.471
High expression	11 (47.8)	14 (58.3)
miR-923
Low expression	8 (34.8)	9 (37.5)	0.846
High expression	15 (65.2)	15 (62.5)

CR – complete response; PR – partial response; SD – stable disease; TP – tumor progression.