Table 2. PORT vs. surgery alone.
| Study | Year | Treatment | Median dosage | N | Survival rate | P | LC/RC rate | p |
|---|---|---|---|---|---|---|---|---|
| Armstrong et al. [22]* | 1990 | PORT S |
56.6 Gy | 46 46 |
51% (5-year DS) 10% |
0.015 | 51.3% (5-year LC) 16.8% |
0.14 |
| Terhaard et al. [15] | 2005 | PORT S |
62.6 Gy | 386 112 |
NS | 91% (10-year LC) 76% |
0.0005 | |
| Storey et al. [23] | 2001 | PORT S |
60.0 Gy | 83 83 |
NS | 88% (5-year LRC) 50% |
<0.05 | |
| North et al. [24] | 1990 | PORT S |
60.0 Gy | 50 19 |
75% (5-year AS) 59% |
0.014 | NS (10-year LC) | <0.001 |
| Le et al. [26] | 1999 | PORT | 60.0 Gy | 52 | 63% (10-year OS) | NS | 88% (10-year LC) | NS |
| Terhaard et al. [27]# | 2003 | PORT S |
62.0 Gy | 385 113 |
NS | NS | 89%( 10-year RC) 67% |
0.03 |
Abbreviation: n, the number of patients; S, surgery; PORT, postoperative radiotherapy; LC, local control; RC, regional control; LRC, locoregional control; DS, determinate survival; AS, actuarial survival; NS: not stated; OS, overall survival; *, for patients with III and IV disease; #, for N+ patient