Table 1. Patient characteristics at baseline.
| Variables | All Patients | Retrospective Cohort | Prospective Cohort | P value |
|---|---|---|---|---|
| Number of patients | 2176 | 1682 | 494 | - |
| Male (%) | 1860 (85.5%) | 1445 (85.9%) | 415 (84.0%) | 0.29 |
| Age (years) | 50.8±11.6 | 50.7±11.8 | 51.4±11.3 | 0.70 |
| Weight (kg) | 62.4±9.8 | 62.3±9.7 | 63.0±10.3 | 0.21 |
| BMI | 22.6±2.6 | 22.5±2.5 | 22.8±2.8 | 0.19 |
| Hemoglobin (g/L) | 140.5±2.4 | 139.3±20.9 | 144.6±18.1 | 0.34 |
| Platelet (109/L) | 140±72 | 136±71 | 143±73 | 0.52 |
| WBC (109/L) | 5.9±2.8 | 5.9±2.9 | 5.9±2.5 | 0.52 |
| TBL (μmol/L) | 20.4±37.6 | 20.5±36.5 | 20.0±37.3 | 0.84 |
| DBL (μmol/L) | 9.3±25.7 | 9.5±27.7 | 8.8±24.9 | 0.23 |
| AST (IU/L) | 56.5±70.9 | 57.5±78.3 | 54.4±72.2 | 0.27 |
| ALT (IU/L) | 57.6±98.3 | 59.7±99.2 | 56.4±97.3 | 0.33 |
| AST/ALT | 1.2±0.9 | 1.2±0.7 | 1.2±0.9 | 0.19 |
| ALP (IU/L) | 114.2±88.6 | 113.7±89.9 | 116.0±84.2 | 0.61 |
| GGT (IU/L) | 110.0±149.3 | 108.1±137.3 | 116.3±143.2 | 0.36 |
| Albumin (g/L) | 40.3±5.5 | 40.1±5.8 | 40.9±4.3 | 0.78 |
| Globulin (g/L) | 29.0±5.5 | 28.8±5.5 | 29.3±5.3 | 0.56 |
| Total protein (g/L) | 69.2±7.3 | 68.9±7.7 | 70.3±6.1 | 0.34 |
| BUN (mmol/L) | 5.9±3.8 | 6.0±3.4 | 5.7±3.7 | 0.70 |
| Scr (μmol/L) | 76.2±20.6 | 76.6±18.9 | 74.9±25.5 | 0.18 |
| Cystatin C (μg/dl) | 105.2±20.9 | 106.0±21.8 | 104.5±19.8 | 0.27 |
| PT (s) | 12.4±2.2 | 12.4±2.5 | 12.3±2.2 | 0.82 |
| APTT (s) | 31.5±6.8 | 31.8±9.1 | 30.4±4.6 | 0.74 |
| INR | 1.12±0.33 | 1.12±0.38 | 1.11±0.10 | 0.32 |
| FIB (mg/cl) | 29.9±13.6 | 29.8±14.1 | 28.9±11.0 | 0.21 |
| Ishak score: 0-1 (%) | 28 (1.3%) | 21 (1.2%) | 7 (1.4%) | <0.001* |
| Ishak score: 2 (%) | 82 (3.8%) | 49 (2.9%) | 33 (6.7%) | |
| Ishak score: 3 (%) | 262 (12.0%) | 194 (11.5%) | 68 (13.8%) | |
| Ishak score: 4 (%) | 327 (15.0%) | 235 (14.0%) | 92 (18.6%) | |
| Ishak score: 5 (%) | 365 (16.8%) | 246 (14.6%) | 119 (24.1%) | |
| Ishak score: 6 (%) | 1112 (51.1%) | 937 (55.7%) | 175 (35.4%) |
*
significant P value.