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. 2016 Dec 10;8(3):4373–4386. doi: 10.18632/oncotarget.13875

Figure 6. Urethane favors the development of Atypical Carcinoids in Rb family deleted lungs.

Figure 6

Analysis of proliferation in urethane treated mice control and TKO tumors of similar size by immunostaining for Ki-67. (A) Quantification. p values were obtained by the Mann Whitney test (p < 0,001). (B) Representative (n ≥ 5) immunostaining. Bars = 20 μm. Analysis of proliferation in urethane treated mice infected and non-infected tumors of similar size by immunostaining for PH3. (C) Quantification. p values were obtained by the Mann Whitney test (p < 0,001) (D) Representative immunostaining. Bars = 50 μm (E) Refinement of diagnosis after quantification of proliferating cells.*Fischer´s exact test p = 0.0003, n = 18. AC: Atypical Carcinoids. TC: Typical Carcinoids.