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. 2016 Dec 15;8(3):4549–4562. doi: 10.18632/oncotarget.13941

Figure 8. Detection of transcriptional activities of HIF-1α and MDR1 in LHBs-overexpressed HepG2 cells.

Figure 8

(A) Confirmation of DNA binding activity of the HIF-1α and nuclear extracts from the samples of LHBs-overexpressed cells using EMSA. (B) Detection of the relative HRE reporter activity by LHBs overexpression. (C) Detection of the relative pGL3-MDR1 reporter activity by LHBs overexpression. (D) Detection of the relative HRE reporter activity by LHBs and/or X protein overexpression. (Bars indicate SD, significant as compared to the control, *P < 0.05.)