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. 2016 Nov 24;8(3):4718–4729. doi: 10.18632/oncotarget.13578

Figure 4. Cytotoxicity test of SPIO and SPIO-R11.

Figure 4

A. The cytotoxicity on T24 cells and B. SV-HUC cells 4 h, 24 h and 72 h after SPIO incubation periods compared with controls at different Fe concentrations. C. The cytotoxicity on T24 cells and (B) SV-HUC cells 4 h, 24 h and 72 h after SPIO-R11 incubation periods compared with controls at different Fe concentrations. The decrease of cell viability was observed only in T24 cells incubated with SPIO-R11 at the highest Fe concentrations of 200 μg/mL after 72 h incubation periods. Columns, mean; bars, SD. *, P < 0.05.