Table 1. Relationship of miR-106a level in cancer tissues and clinicopathological factors in patients with colorectal cancer.
| colorectal cancer | 138 cases | miR-106aa | |
|---|---|---|---|
| n | % | ||
| Sex | |||
| Male | 92 | 66.7 | 1.491(0.460,2.010) |
| Female | 46 | 33.3 | 1.326(0.449,1.855) |
| p | 0.887 | ||
| Age (years) | |||
| >60 | 67 | 48.6 | 1.434(0.514,1.381) |
| ≤60 | 71 | 51.4 | 1.438(0.406,2.015) |
| P | 0.486 | ||
| Tumor size(cm) | |||
| <5 | 60 | 43.5 | 1.015(0.479,1.707) |
| ≥5 | 78 | 56.5 | 1.760(0.447,2.729) |
| P | 0.029* | ||
| Preoperative CEA level | |||
| <5 ng/mL | 82 | 59.4 | 0.920(0.487,1.245) |
| ≥5 ng/mL | 56 | 40.6 | 2.192(0.417,3.986) |
| P | 0.013* | ||
| Histologic grade | |||
| well differentiated | 102 | 73.9 | 1.401(0.438,2.011) |
| poorly differentiated | 36 | 26.1 | 1.536(0.674,0.995) |
| P | 0.356 | ||
| T classification | |||
| T1+T2 | 48 | 34.8 | 1.101(0.342,1.822) |
| T3+T4 | 90 | 65.2 | 1.615(0.523,2.034) |
| P | 0.004* | ||
| TNM stage | |||
| I | 18 | 13 | 1.383(0.396,2.258) |
| II | 31 | 22.5 | 1.044(0.338,1.706) |
| III | 64 | 46.4 | 1.459(0.514,1.768) |
| IV | 25 | 18.1 | 1.901(0.507,3.943) |
| p | 0.101 | ||
| Lymphatic invasion | |||
| Negative | 53 | 38.4 | 1.549(0.414,2.418) |
| Positive | 85 | 61.6 | 1.365(0.481,1.699) |
| p | 0.509 | ||
| Distant metastasis | |||
| Negative | 104 | 75.4 | 1.395(0.448,1.822) |
| Positive | 34 | 24.6 | 1.562(0.601,2.622) |
| p | 0.401 | ||
aMean of relative expression with 25th–75th percentile is recorded in parentheses, use nonparametric test (Mann–Whitney U test between two groups and Kruskal–Wallis H test for three or more groups); *p<0.05.