Figure 1. MiR-433-3p and miR-433-5p are down-regulated in malignant glioma.
A. The relative miR-433-3p and miR-433-5p expression levels in 6 normal brain tissues and 12 glioma tissues were analyzed by quantitative RT-PCR. *P < 0.05 versus Normal. B. Real-time PCR analysis of miR-433-3p and miR-433-5p expression in various glioma cell lines (U251, U87, LN229, SNB19 and LN308). C. and D. The efficiency of miR-433-3p and miR-433-5p mimics in U251 and U87 cells was confirmed by quantitative RT-PCR. *P < 0.05 versus Scramble. All experiments were repeated three times. All data are shown as mean ± SD.