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. 2016 Dec 22;8(3):5160–5178. doi: 10.18632/oncotarget.14107

Figure 6. Schematic representation of the signal propagation algorithm used.

Figure 6

Upper part: the three types of activity transmitted: left) the combination of two activations, center) the combination of an activation and an inhibition and right) the combination of two inhibitions. Central part: the normalized values of gene expression are assigned to the corresponding nodes in the circuits. Lower part: the signal starts with a value of 1 in the receptor node A and is propagated by multiplying the weights assigned to each node in the central part following the rules depicted in the upper part.