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. 2016 Dec 23;8(3):5247–5255. doi: 10.18632/oncotarget.14127

Figure 1. Lethal doses of IFNα are able to eradicate a liver metastases model of colon cancer.

Figure 1

A. IFNα serum levels in mice were determined by ELISA one week after being treated by different doses of AAV-IFNα (n = 3, mice per group). B. Kaplan-Meier plot representing the survival of mice treated by different doses of AAV-IFNα (n = 3, mice per group). C. Schematic representation of a mouse model for liver metastases from colon cancer (left panel). Colon cancer cells (MC38) were injected into the liver of mice and, four days later, different doses of AAV-IFNα were intravenously administrated (n = 6, mice per group). Survival of mice is represented in a Kaplan-Meier plot (right panel).