Table 2. Univariate and multivariate analysis of prognostic factors for overall survival rate.
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| Variable | HR (95%CI) | P | HR (95%CI) | P | |
| Age | 0.994 (0.980-1.009) | 0.442 | |||
| Gender (male) | 1.030 (0.826-1.286) | 0.792 | |||
| HBsAg (positive) | 0.881 (0.583-1.331) | 0.547 | |||
| Liver cirrhosis | 0.945 (0.781-1.144) | 0.564 | |||
| Child–Pugh B | 3.081 (1.924-7.510) | <0.001 | |||
| ICG-R15 | 1.088 (1.046-1.132) | <0.001 | 1.046 (1.002-1.092) | 0.042 | |
| BCLC A | 7.445 (1.844-30.139) | 0.005 | |||
| ALT | 0.999 (0.995-1.003) | 0.690 | |||
| TB | 1.016 (1.001-1.032) | 0.039 | |||
| AKP | 1.001 (0.997-1.005) | 0.569 | |||
| GGT | 1.001 (0.999-1.003) | 0.336 | |||
| Albumin | 0.951 (0.913-0.989) | 0.013 | |||
| INR | 5.649 (1.640-19.455) | 0.006 | |||
| Platelet | 1.000 (0.997-1.002) | 0.761 | |||
| AFP | 1.000 (1.000-1.000) | 0.121 | |||
| Tumor size | 1.216 (1.138-1.299) | <0.001 | 1.113 (1.023-1.210) | 0.013 | |
| Operation time | 1.001 (1.000-1.003) | 0.137 | |||
| Blood loss | 1.000 (1.000-1.001) | 0.004 | |||
| Anatomical resection | 0.768 (0.646-0.914) | 0.003 | 0.767 (0.623-0.944) | 0.012 | |
| Tumor differentiation (moderate/poor) |
2.427 (1.340-4.394) | 0.003 | |||
| Low-MVI | 1.691 (1.090-2.621) | 0.019 | |||
| High-MVI | 3.764 (2.527-5.697) | <0.001 | 2.766 (1.675-4.566) | <0.001 | |
| Transfusion (yes) | 1.760 (1.211-2.558) | 0.003 | |||
HBsAg, hepatitis B surface antigen; ICG-R15, indocyanine green retention rate at 15 minutes; ALT, alanine aminotransferase; TB, total bilirubin; GGT, gamma glutamyl transpeptidase; AKP, alkaline phosphatase; INR, International Normalized Ratio; AFP, alpha-fetoprotein; MVI, microvascular invasion.