Table 1. Changes of cell membrane electrical properties of colon projecting DRG neurons in bowel obstruction.
Shown here are parameters of cell membrane electrical properties other than shown in Fig. 1.
| Size (µm) |
Cm (pF) |
Rin (MΩ) |
AP (2× rheobase) (# in 300 ms) |
Threshold (mV) |
Amplitude (mV) |
Overshoot (mV) |
Duration (ms) |
||
|---|---|---|---|---|---|---|---|---|---|
| Sham | 28.1±0.64 | 50.3±1.49 | 446.5±26.07 | 1.1±0.03 | −32.1±1.19 | 95.6±2.34 | 44.5±1.98 | 2.6±0.13 | |
| BO | 1 d | 27.2±0.60 | 47.7±1.38 | 514.3±30.14 | 1.2±0.05 | −32.9±1.04 | 91.1±1.79 | 43.7±1.98 | 2.4±0.08 |
| 3 d | 27.3±0.75 | 49.3±1.42 | 451.4±42.92 | 1.5±0.10 * | −32.0±1.23 | 91.4±3.11 | 42.7±3.05 | 2.6±0.09 | |
| 7 d | 28.5±0.68 | 51.7±1.68 | 450.5±30.01 | 2.2±0.15 * | −30.2±1.81 | 92.9±3.44 | 45.2±2.92 | 2.7±0.18 | |
Size, neuron diameter; Cm, cell capacitance; Rin, input resistance; AP, action potential; Threshold, AP threshold; Amplitude, AP amplitude; Overshoot, AP overshoot; Duration, AP duration. Neurons recorded in each group: n = 11/51 (numbers of rats/neurons) in sham; n = 6/57 for BO day 1 (1 d); n = 5/26 for BO day 3 (3 d); n = 5/31 for BO day 7 (7 d). Data is expressed as mean ± SEM.
*
P < 0.05 vs. sham.