Table I.

Comparative regimen pricing of r-pFVIII immediately post-procedure to bypassing agents rFVIIa and aPCC.

Product	Regimen Price	Regimen*	Total Doses	Total Usage
r-pFVIII	$ 103,300	170 IU/kg, subsequently administered doses were 100 IU/kg	12	22,121 IU
rFVIIa	$ 63,141	270 mcg/kg initial dose followed by 90 mcg/kg q2 hours with subsequent spacing	22	37,585 mcg
aPCC	$ 16,269	100 IU/kg initial dose followed by 50 IU/kg q6 hours	10	9,571 IU

^*Estimated rFVIIa and aPCC regimens based on typical site practice for a patient post-procedure with good hemostasis for the duration (62 hours) that r-pFVIII was used.