Skip to main content
. Author manuscript; available in PMC: 2017 Jul 23.
Published in final edited form as: Nature. 2017 Jan 23;543(7645):378–384. doi: 10.1038/nature21386

Figure 1. Somatic alterations in cervical cancer and associations with molecular platform features.

Figure 1

CESC samples are ordered by histology and mutation rate (top panel), clinical and molecular platform features (second panel), significantly mutated genes (SMGs; third panel), and select somatic copy number alterations (SCNAs; fourth panel) are presented. SMGs are ordered by the overall mutation frequency and color-coded by mutation type. Novel SMGs identified in squamous cell carcinomas are labeled in turquoise text. The number of APOBEC signature mutations (red) and other mutations (blue) present in every SMG is plotted to the right of the SMG panel and the number of gene level SCNAs across all genes is plotted as gain (red) and loss (blue) to the right of the SCNA panel.