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. 2017 Feb 7;8(8):12649–12663. doi: 10.18632/oncotarget.15172

Figure 2. Overexpression of Dvl2 prevents joint destruction in the knee joint of CIA rats.

Figure 2

A. H&E and safranin O-fast green staining of knee joints (n = 5/group). B. Histopathological scores of synovial inflammation and cartilage destruction (n = 5/group). C. Micro-CT images of knee joints (n = 3/group). D. The measurement of bone volume/tissue volume (BV/TV), bone volume/total tissue volume (BS/BV), and bone mineral density (BMD) (n = 3/group). *p < 0.05, NSp > 0.05; CIA, collagen-induced arthritis; Normal, healthy rats without CIA; Dvl2, the knee joints of CIA rats injected with lentivirus-Dvl2; Control, the knee joints of CIA rats injected with lentivirus-control. Scale bars: 500 μm.