Table 4. Relapse free survival and overall survival univariate log-rank and cox regression analysis for association of clinical parameters and CD74/MHCII combined status in the Basal-like subgroup.
A. Recurrence free survival | Univariate | Multivariate | |||
---|---|---|---|---|---|
Parameter | Comparison | HR (95% CI) | p-value | HR (95% CI) | p-value |
Age at diagnosis (yrs) | > 35 vs ≤ 35 | 0.79 (0.22–3.01) | 0.751 | 0.81 (0.15–4.34) | 0.809 |
Tumour size (cm) | > 2 cm vs ≤ 2 cm | 2.88 (0.95–5.50) | 0.070 | 8.02 (1.01–63.78) | 0.049 |
Nodal status | pos vs neg | 1.79 (0.78–3.92) | 0.155 | 2.66 (0.95–7.44) | 0.062 |
Tumor grade | 2 vs 1 | 0.51 (0.12–2.82) | 0.501 | 2.72 (0.16–47.62) | 0.492 |
3 vs 1 | 1.07 (0.13–8.76) | 0.946 | 1.77 (0.63–4.97) | 0.278 | |
CD74+MHCII expression | high vs low | 0.29 (0.17–0.90) | 0.031 | 0.29 (0.07–1.26) | 0.099 |
B. Overall survival | Univariate | Multivariate | |||
Parameter | Comparison | HR (95% CI) | p-value | HR (95% CI) | p-value |
Age at diagnosis (yrs) | > 35 vs ≤ 35 | 0.77 (0.22–2.86) | 0.714 | 0.84 (0.17–4.18) | 0.829 |
Tumour size (cm) | >2 cm vs ≤ 2 cm | 2.36 (0.88–4.72) | 0.100 | 3.73 (0.82–17.05) | 0.090 |
Nodal status | pos vs neg | 1.59 (0.72–3.41) | 0.193 | 1.95 (0.75–5.07) | 0.172 |
Tumor grade | 2 vs 1 | 0.56 (0.12–3.22) | 0.572 | 1.68 (0.14–20.55) | 0.686 |
3 vs 1 | 1.02 (0.14–7.59) | 0.983 | 1.75 (0.67–4.59) | 0.256 | |
CD74+MHCII expression | high vs low | 0.26 (0.17–0.81) | 0.014 | 0.35 (0.11–1.18) | 0.091 |