Figure 8. The level of main target proteins were analyzed when cells were exposed to drugs for 24 h.

MV4-11, MOLM-13 and primary AML cells were treated with 8 nM HHT and/or 2.5 μM ibrutinib for 24 h. Western blot analysis was conducted for FLT3, p-FLT3, BTK, and p-BTK223 protein levels.