Table 2. FISH analysis of recurrently amplified RTK genes.
Gene | Sample | Amplification | |
---|---|---|---|
DD area | WD area | ||
DDR2 | WDLPS_04T | NA | + |
WDLPS_08T | NA | ++ | |
WDLPS_17T | NA | ++ | |
WDLPS_18T | NA | ++ | |
WDLPS_19T | NA | ++ | |
DDLPS_16T | ++ | ++ | |
ERBB3 | WDLPS_09T | NA | + |
DDLPS_09T | ++ | ++ | |
DDLPS_27T | ++ | + | |
DDLPS_33T | ++ | NS | |
NTRK1 | WDLPS_14T | NA | ++ |
WDLPS_19T | NA | ++ | |
DDLPS_05T | ++ | NS | |
FGFR3 | DDLPS_08T | ++ | NS |
DDLPS_34T | ++ | NE | |
ROS1 | DDLPS_01T | ++ | + |
DDLPS_40T | ++ | – |
DD, dedifferentiated; WD, well differentiated; NA, not associated; NS, no sample, NE, not evaluable; “++”, positive in many tumor cells; “+”, positive in a small subset of tumor cells; “–”, negative.