Table 1. Characteristics of DLBCL patients #1 and #2.
Name | #1 | #2 |
---|---|---|
Origin of cells | Lymph node | Peripheral blood |
Age | 29 | 75 |
MYC rearrangement | + | + |
BCL2 rearrangement | - | + |
MYC protein in IHC | - | + |
BCL2 protein in IHC | + | + |
CNS invasion | + | + |
1st line treatment | DA-EPOCH-R | R-CHOP |
Response | Progressive disease | Partial response |
Overall Survival (Mo) | 5 | 31 |
Progression-free Survival (Mo) | 1 | 10 |
Cytogenetic analyses | 46, XY, add(1)(q21), add (3)(p13), add(4)(p16),?t(8;22)(q24;q11.2), add(17)(p11.2) | 48, XX, +X, add(1)(p36.1), add (5)(q31),add(7)(q22), t(8;14)(q24;q32), del(13)(q?), t(14;18)(q32.q21),+der(18)t(14;18),-22, -22,+der(?)t(?.q21),+mar1 |