Table 2. Allele frequencies in cases and controls and odds ratio estimates for CHD.
SNP ID | Gene(s) | Band | Alleles Aa/B | MAF | HWEp | ORs | 95% CI | p | |
---|---|---|---|---|---|---|---|---|---|
Case | Control | ||||||||
Male | |||||||||
rs11206831 | PPAP2B | 1p32.2 | T/C | 0.050 | 0.055 | 1 | 0.909 | 0.559-1.478 | 0.700 |
rs1759752 | PPAP2B | 1p32.2 | C/G | 0.220 | 0.168 | 0.8558 | 1.401 | 1.066-1.841 | 0.015* |
rs1930760 | PPAP2B | 1p32.2 | T/C | 0.490 | 0.467 | 0.4733 | 1.093 | 0.881-1.356 | 0.418 |
rs12566304 | PPAP2B | 1p32.2 | A/C | 0.132 | 0.148 | 0.1561 | 0.877 | 0.643-1.198 | 0.410 |
rs914830 | PPAP2B | 1p32.2 | T/C | 0.324 | 0.329 | 0.8172 | 0.976 | 0.776-1.229 | 0.838 |
Female | |||||||||
rs11206831 | PPAP2B | 1p32.2 | T/C | 0.050 | 0.045 | 1 | 1.011 | 0.530-1.928 | 0.975 |
rs1759752 | PPAP2B | 1p32.2 | C/G | 0.209 | 0.165 | 1 | 1.338 | 0.950-1.883 | 0.094 |
rs1930760 | PPAP2B | 1p32.2 | T/C | 0.442 | 0.498 | 0.7299 | 0.799 | 0.610-1.046 | 0.102 |
rs12566304 | PPAP2B | 1p32.2 | A/C | 0.161 | 0.148 | 0.1653 | 1.099 | 0.759-1.591 | 0.619 |
rs914830 | PPAP2B | 1p32.2 | T/C | 0.339 | 0.348 | 0.1621 | 0.961 | 0.724-1.246 | 0.784 |
MAF, minor allelic frequency; HWE, Hardy-Weinberg Equilibrium; ORs, odds ratios; CI: confidence interval.
a Minor allele; *p ≤ 0.05 indicates statistical significance;