Table 2. Expression levels of the five lncRNAs and their AUC values in training set and validation set.
Group | LncRNA | Mean (SD)in NT | Mean (SD)in LSCC | p-Value | AUC (SE) | Sensitivity(%) | Specificity(%) |
---|---|---|---|---|---|---|---|
Training Set: | ENST00000453324 | 1.19 (1.63) | 3.74 (3.94) | 0.001481 | 0.76 (0.07) | 69 | 84 |
NR_028500 | 0.98 (1.00) | 2.36 (2.17) | 0.001293 | 0.70 (0.07) | 73 | 65 | |
UC011CLY.2 | 3.37 (3.36) | 9.08 (5.85) | 0.000013 | 0.77 (0.06) | 84 | 66 | |
NR_046326 | 2.16 (2.44) | 6.91 (5.40) | 0.000040 | 0.79 (0.06) | 84 | 74 | |
ENST00000441841 | 4.78 (5.20) | 13.48 (11.01) | 0.000288 | 0.76 (0.06) | 73 | 73 | |
Validation Set: | ENST00000453324 | 2.02 (2.18) | 5.42 (4.49) | 0.000010 | 0.77 (0.05) | 64 | 80 |
NR_028500 | 2.32 (2.66) | 6.41 (6.16) | 0.000191 | 0.73 (0.06) | 75 | 68 | |
UC011CLY.2 | 3.94 (4.02) | 12.64 (10.02) | 0.000003 | 0.80 (0.05) | 73 | 80 | |
NR_046326 | 4.12 (4.53) | 10.65 (8.36) | 0.000026 | 0.77 (0.05) | 79 | 71 | |
ENST00000441841 | 8.10 (10.80) | 20.10 (16.92) | 0.000006 | 0.80 (0.07) | 86 | 70 |
Abbreviations: AUC: area under the receiver operating characteristic curve; SD: standard deviation; SE: standard error. Both the p value and AUC were obtained using the β-actin normalized values.