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. 2017 Jan 5;8(8):13357–13366. doi: 10.18632/oncotarget.14528

Figure 2. THUMPD1 expression and subcellular localization in breast cancer cell lines.

Figure 2

THUMPD1 expression was higher in most tested breast cancer cell lines compared to normal breast cells (MCF-10A), but was lower in MDA-MB-231 and MDA-MB-468 cells (A). Immunofluorescence analyses indicated that THUMPD1 was mainly localized in MCF-10A cell nuclei, and in both nuclei and cytoplasm of breast cancer cells (B). Immunofluorescence analysis of THUMPD1-myc expression in MCF-7 cells using a Myc-tag antibody (C). Overexpressed THUMPD1 was predominantly localized in the cytoplasm. No positive signal was detected in untransfected cells. Magnification, ×600.