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. 2017 Jan 5;8(8):13357–13366. doi: 10.18632/oncotarget.14528

Figure 4. THUMPD1 enhanced breast cancer cell invasion and migration in vivo and in vitro.

Figure 4

Cell migration (A) Cell invasion (B) THUMPD1 overexpression in MCF-7 and MDA-MB-468 cells enhanced migration and invasion, while THUMPD1 knockdown in MCF-7 and BT-549 cells inhibited migration and invasion. Mice injected with THUMPD1-overexpressing MCF-7 cells developed more pulmonary metastases than controls (C) *p < 0.05.