Table 1. Correlation of THUMPD1 overexpression with clinicopathological features in 146 cases breast cancer.
| Clinicopathological factors | The overall expression | Cytosolic expression | Nuclear expression | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | positive | negative | p | N | positive | negative | p | N | positive | negative | p | |
| Age | ||||||||||||
| < 52 | 75 | 48 | 27 | 0.499 | 75 | 29 | 46 | 0.733 | 75 | 27 | 48 | 0.734 |
| ≥ 52 | 71 | 41 | 30 | 71 | 25 | 46 | 71 | 28 | 43 | |||
| TNM classification | ||||||||||||
| I+II | 122 | 68 | 54 | 0.003 | 122 | 36 | 86 | < 0.001 | 122 | 44 | 78 | 0.368 |
| III | 24 | 21 | 3 | 24 | 18 | 6 | 24 | 11 | 13 | |||
| Lymph node metastasis | ||||||||||||
| positive | 30 | 26 | 4 | 0.001 | 30 | 20 | 10 | < 0.001 | 30 | 16 | 14 | 0.058 |
| negative | 116 | 63 | 53 | 116 | 34 | 82 | 116 | 39 | 77 | |||
| Triple-negative(ER,PR,Her-2) | ||||||||||||
| positive | 82 | 54 | 28 | 0.177 | 82 | 20 | 44 | 0.23 | 82 | 31 | 51 | 1 |
| negative | 64 | 35 | 29 | 64 | 34 | 48 | 64 | 24 | 40 | |||