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. 2017 Jan 6;8(8):13387–13399. doi: 10.18632/oncotarget.14534

Table 3. The diagnostic performances of SWS imagine in predicting thyroid malignancy with different sizes.

SWS indices Cut-off value SEN (%) SPE (%) PPV (%) NPV (%) ACU (%) AUC& P* P# P& P^
Nodule size ≤ 10 mm (n = 123) 0.528 0.083 0.031 0.003
E-max kpa 24.4 76.9 76.2 60.0 87.7 76.4 0.776 (0.692,0.846)
m/s 2.82 76.9 72.6 56.6 87.1 74.0 0.788 (0.705,0.857)
E-mean kpa 19.3 43.6 88.1 63.0 77.1 74.0 0.696 (0.607,0.776)
m/s 2.61 41.0 89.3 64.0 76.5 74.0 0.672 (0.581,0.754)
11 ≤ Nodule size ≤ 20 mm (n = 132) 0.668 0.334 0.583 0.435
E-max kpa 46.9 80.0 91.5 85.1 88.2 87.1 0.894 (0.829,0.941)
m/s 3.92 78.0 92.7 86.7 87.4 87.1 0.895 (0.830,0.942)
E-mean kpa 22.5 74.0 91.5 84.1 85.2 84.8 0.883 (0.815,0.932)
m/s 2.45 82.0 84.1 76.0 88.5 83.3 0.876 (0.808,0.927)
Nodule size >20 mm (n = 67) 0.193 0.685 0.251 0.911
E-max kpa 52.4 88.2 82.0 62.5 95.3 83.6 0.810 (0.696,0.896)
m/s 4.13 94.1 84.0 66.7 97.7 86.6 0.883 (0.781,0.949)
E-mean kpa 27.8 70.6 92.0 75.0 90.2 86.6 0.886 (0.785,0.951)
m/s 2.67 76.5 88.0 68.4 91.7 85.1 0.877 (0.774,0.945)

AUC=area under receiver curve; ACU,=accuracy; NPV=negative predictive value; PPV=positive predictive value; SEN=sensitivity; SPE= specificity; SWS=shear wave speed; E-max = the max value of shear wave speed imagine; E-mean = the mean value of shear wave speed imagine ;

& Note–numbers in parentheses are 95% confidence intervals (CI)

P* AUC in comparison with that of E-max between elasticity and speed

P# AUC in comparison with that of E-mean between elasticity and speed

P& AUC in comparison with that of E-max elasticity and E-mean elasticity

P^ AUC in comparison with that of E-max speed and E-mean speed