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. 2017 Jan 11;8(8):13586–13599. doi: 10.18632/oncotarget.14600

Figure 2. HnRNP-L stimulates proliferation and accelerates the cell cycle of UM-UC-3 and EJ cell lines.

Figure 2

(A) When cultured in the plate colony formation assay, colony formation by hnRNP-L transfected cells was obviously enhanced, and decreased in sh-hnRNP-L transfected cells; (B) In the CCK-8 assay, cell viability was increased by hnRNP-L and decreased by sh-hnRNP-L; (C) Flow cytometry revealed that sh-hnRNP-L transfected cells were arrested in G0/G1 phase; Conversely, hnRNP-L transfected cells were accelerated into the S phase; (D) Vertical bars presented the statistical analysis of the cell cycle results. All the assays were each performed three times independently. The data are shown as mean ± SD *p < 0.05; **p < 0.01; ***p < 0.001.