Figure 3. HnRNP-L accelerates tumor growth in vivo.
(A) Gross observation of xenograft tumor size in NOD/SCID mice; (B) hnRNP-L overexpression promotes tumour growth, while silencing of hnRNP-L inhibited the tumor growth; (C) Histological analysis of tumor weight (vs. Control). (D) H&E-stained paraffin-embedded sections obtained from xenografts. (E) IHC staining for hnRNP-L of in xenograft tumors. (F–G) IHC staining for Ki-67 in xenograft tumors and the histogram exhibited the Ki-67 index (%). (H) The infection efficacy of lentivirus with GFP in vivo. Original magnification (×400). The data are shown as mean ± SD *p < 0.05; **p < 0.01; ***p < 0.001.