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. 2017 Jan 11;8(8):13586–13599. doi: 10.18632/oncotarget.14600

Figure 4. HnRNP-L expression affected the apoptosis in UM-UC-3 and EJ cells.

Figure 4

(A) HnRNP-L knockdown increased the rate of apoptosis by flow cytometry; Whereas hnRNP-L overexpression decreased the rate of apoptosis by flow cytometry; (B) Statistics analysis of the apoptosis rate in each group (n = 3, Student's t-test, p < 0.05). Means ± SD were shown, *p < 0.05; **p < 0.01; ***p < 0.001; (C) Western blot shown that hnRNP-L knockdown increased the expression caspase-9, caspase-6, caspase-3 and Bcl2L1, whereas the expression of Bcl-2 and PARP-1 was decreased; (D) HnRNP-L overexpression reversed all the changes on the apoptosis pathway. GAPDH served as loading control.