Figure 1. Imetelstat radiosensitizes Kyse410 and Kyse520 cells by using clonogenic cell survival following imetelstat and/or X-ray irradiation (2, 4, 6 and 8 Gy).

(A) shows survival fraction as a function of imetelstat, radiation dose and their combination. (B) shows survival plots as a function of radiation dose with or without imetelstat. Survival data were fitted to S = exp (-αD-βD2) where D is the dose in Gy and α and β are fitting parameters, n ≥ 6, Error bars represent standard deviation. All imetelstat treatment had P-values less than 0.05 except imetelstat + 6 Gy treatment for Kyse410.