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. 2017 Jan 10;8(7):10809–10821. doi: 10.18632/oncotarget.14580

Figure 2. BCR-ABL upregulates Gadd45a expression.

Figure 2

A. Real time PCR analysis using taqman probe, of Gadd45a mRNA transcripts in WT BM cells transduced with either MIG or BCR-ABL expressing retroviral vector that has been treated or untreated with 5uM Imatinib. Expression is relative to WT/MIG treated sample. B. Real time PCR analysis using taqman probe, of Gaddd45a mRNA transcripts in K562 cells treated and untreated with Imatinib. Expression was determined by using 18s rRNA as an endogenous control in AB Step one plus real time PCR machine. Data from 3 experiments is shown. Error bars represent SD for each group (* P < 0.05).