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. 2017 Jan 10;8(7):10809–10821. doi: 10.18632/oncotarget.14580

Figure 5. Loss of Gadd45a does not affect the number of Normal Hematopoietic stem cells as well as homing and engraftment of bone marrow cells.

Figure 5

A. Bar graph representation of flow cytometric data showing average LSK cells from 6 independent experiments. Differences between normal stem cells in WT and Gadd45a−/− mice were not significant. P > 0.05 B. FACS of donor derived CD45.2 (WT or Gadd45a−/−) cells in CD45.1 mice, 3 hrs post BMT. Bar graph shows average percent CD45.2 cells from 3 independent experiments (n = 5 per genotype). Bars ± SEM P > 0.05 C.&D. Summary of flow data from competitive repopulation experiments showing Gr1 and CD11b myeloid markers CD45.1+Gr1+, CD45.2+Gr1+ve, CD45.1+cd11b+ and CD45.2+cd11b+ve cells. P > 0.05 Results are representative of 3 independent experiments in each group (n = 4 per genotype).