Table 1. Patient characteristics.
| All (n = 624) | HBeAg (+) (n = 489) | HBeAg (−) (n = 135) | p value* | |
|---|---|---|---|---|
| Gender, M/F | 428/196 | 330/159 | 98/37 | 0.30 |
| Age, years | 32.79 ± 11.68 | 30.94 ± 10.59 | 39.51 ± 12.95 | < 0.001 |
| PLT, 109/L | 188.28 ± 61.00 | 195.27 ± 58.33 | 162.95 ± 63.87 | < 0.001 |
| ALT, U/L | 75 (40–152) | 72 (38–144) | 99 (47–169) | 0.15 |
| AST, U/L | 43 (26–85) | 40 (25–80) | 58 (34–97) | 0.32 |
| TBIL, μmol/L | 19.80 ± 16.22 | 19.06 ± 15.12 | 22.51 ± 19.55 | 0.03 |
| HBV DNA, log10IU/mL | 6.69 ± 1.52 | 7.16 ± 1.18 | 4.99 ± 1.40 | < 0.001 |
| HBsAg, log10IU/mL | 3.88 ± 0.71 | 4.00 ± 0.70 | 3.46 ± 0.57 | < 0.001 |
| qAnti-HBc, log10IU/mL | 4.23 ± 0.99 | 4.14 ± 1.06 | 4.52 ± 0.61 | < 0.001 |
| HBV genotype, (%)** | 0.23 | |||
| B | 53 (8.95) | 45 (9.51) | 8 (6.72) | |
| C | 535 (90.37) | 425 (89.85) | 110 (92.44) | |
| D | 3 (0.51) | 3 (0.63) | 0 (0.00) | |
| B/C | 1 (0.17) | 0 (0.00) | 1 (0.84) |
*
HBeAg (+) vs. HBeAg (−).
**
32 patients could not be genotyped with our assay.