Table 2. Multiple logistic regression analysis of factors associated with significant fibrosis in HBeAg (+) patients.
Parameter | Not significant | Significant | P | Multivariate | |||
---|---|---|---|---|---|---|---|
OR | 95% CI | Wald | P | ||||
Age, years | 27.72 ± 8.83 | 35.79 ± 11.19 | < 0.001 | 1.07 | 1.04–1.09 | 28.10 | < 0.001 |
PLT, 109/L | 211.00 ± 51.48 | 171.56 ± 60.14 | < 0.001 | 0.99 | 0.99–1.00 | 17.60 | < 0.001 |
ALT, U/L | 76.00 ± 94.29 | 292.45 ± 386.03 | < 0.001 | 1.00 | 1.00–1.01 | 2.24 | 0.135 |
AST, U/L | 43.82 ± 51.58 | 186.44 ± 282.54 | < 0.001 | 1.01 | 1.00–1.01 | 3.43 | 0.064 |
TBIL, μmol/L | 16.27 ± 9.29 | 23.26 ± 20.37 | < 0.001 | 1.01 | 0.98–1.03 | 0.15 | 0.696 |
HBV DNA, log10IU/mL | 7.42 ± 1.05 | 6.77 ± 1.26 | < 0.001 | 0.83 | 0.66–1.04 | 2.64 | 0.104 |
HBsAg, log10IU/mL | 4.16 ± 0.70 | 3.77 ± 0.63 | < 0.001 | 0.72 | 0.49–1.04 | 3.03 | 0.082 |
qAnti-HBc, log10IU/mL | 3.84 ± 1.14 | 4.60 ± 0.72 | < 0.001 | 1.77 | 1.28–2.45 | 11.85 | 0.001 |