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. 2017 Jan 4;8(7):11173–11186. doi: 10.18632/oncotarget.14491

Figure 2. Overexpression of MDR3 and MRP1 in tumour samples correlated with poor prognosis.

Figure 2

(A) Significantly higher expression of MDR3 and MRP1 in high-risk WT than normal kidney, low and intermediate risk tumours. (B) Blastemal predominant tumoural subtype presented more MDR3 and MRP1 expression levels than kidney, low- and intermediate-risk tumours. (C) Protein expression of MDR3 and MRP1 in normal kidney and WT samples. High-risk WT samples had more MDR3 and MRP1 protein expression than kidneys and intermediate risk tumours. (D) Significant positive correlation between MDR3 and MRP1 in WT but not in normal kidney samples. For all the analyses, *p < 0.05; **p < 0.01; ***p < 0.001. NS, not significant.