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. 2017 Jan 4;8(7):11228–11238. doi: 10.18632/oncotarget.14495

Figure 3. EMT reversion by IL-6 Pathway Blockade.

Figure 3

(A) Quantitative PCR detection of the EMT biomarkers mRNA in each cell line. (B) Western-blotting detection of IL-6 pathway inhibition and EMT biomarkers expression change in Eca109 cells exposed to IR, AG490 or sh-Twist. (C) Scratch assay detection of attenuated invasiveness of EMT-Eca109 cells under AG490 or sh-Twist treatment (left) and their quantitative analysis (right). (D) Transwell invasion assay detection of impaired migration and invasion ability of EMT-Eca109 cells under AG490 or sh-Twist treatment (left) and their quantitative analysis (right).