Figure 5. Exosome-specific proteins can be detected on exosomes from MCF-7 breast cancer cells.

Cells were treated for 48 hr with SMRwt peptide alone or combined with paclitaxel or cisplatin. (A) Expression of exosome proteins by Western blot analysis and (B) Exosome numbers were measured by NanoSight and (C) Densitometry analysis showing relative intensity of bands. Data represent the mean ± SD of three independent experiments. Significant differences relative to treatment with peptide are indicated as follows: *p < 0.01, **p < 0.001, ***p < 0.0001.