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. 2017 Jan 5;8(7):11356–11371. doi: 10.18632/oncotarget.14529

Figure 1. MiR-410 increased the expressions of stem cells markers Oct4, Sox2, Nanog, CXCR4 and cells surface markers CD44 and CD166 in NSCLC cells.

Figure 1

(A) and (B) Expressions of miR-410 were detected by qRT-PCR in miR-410 overexpression (A) or knock-down (B) stable cells derived from A549 and H1299 cells. (C–E) and (F) Expressions of CXCR4 C., Nanog D., Oct4 (E) and Sox2 (F) were detected by qRT-PCR respectively in miR-410 overexpression or knock-down stable cells derived from A549 and H1299 cells. (G) and (H) Protein expression of CXCR4, Nanog, Oct4, Sox2, and stem cells surface markers CD44 and CD166 were detected by western blotting respectively in miR-410 overexpression or knock-down stable cells derived from A549 (G) and H1299 (H) cells. Mic and Mic-NC, miR-410 overexpression stable cells and its matched NC control stable cells; Inh and Inh-NC, miR-410 knock-down stable cells and its matched NC control stable cells. *P < 0.05; **P < 0.01; ***P < 0.001. *compared with the relative NC control.