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. 2017 Jan 5;8(7):11356–11371. doi: 10.18632/oncotarget.14529

Figure 2. MiR-410 augmented sphere formation and proliferation abilities of NSCLC.

Figure 2

(A and B) Sphere formation assays of miR-410 stable overexpressed or knock-down cells derived from A549 (A) and H1299 (B) cells. Mic and Mic-NC, miR-410 overexpression stable cells and its matched NC control stable cells; Inh and Inh-NC, miR-410 knock-down stable cells and its matched NC control stable cells. (C and D) Colony formation assays of miR-410 overexpression or knock-down stable cells derived from A549 C. and H1299 (D) cells. Mic and Mic-NC, miR-410 overexpression stable cells and its matched NC control stable cells; Inh and Inh-NC, miR-410 knock-down stable cells and its matched NC control stable cells. (E and F) MTT assays of miR-410 overexpression or knock-down stable cells derived from A549 (E) and H1299 (F) cells. Mic and Mic-NC, miR-410 overexpression stable cells and its matched NC control stable cells; Inh and Inh-NC, miR-410 knock-down stable cells and its matched NC control stable cells. (G–I) and (J) Images (G) the growth curves (H) the relative growth rate (I) and Ki67 immunohistochemical staining (J) of subcutaneous tumor. Mic and Mic-NC, mice treated with miR-410 overexpression stable cells and its matched NC control stable cells; Inh and Inh-NC, mice treated with miR-410 knock-down stable cells and its matched NC control stable cells. *P < 0.05; **P < 0.01; ***P < 0.001. *compared with the relative NC control.