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. 2016 Dec 15;8(7):11400–11413. doi: 10.18632/oncotarget.13940

Figure 4. miR-17-5p is decreased in radioresistant EAC cells in vitro and in vivo.

Figure 4

A. Digital gene expression analysis, demonstrated as heat maps, of miR-17~92 family members significantly altered in OE33 R ALDH+ve populations, when compared to OE33 R ALDH-ve populations (red and green boxes indicate upregulation and downregulation, respectively) B. miR-17-5p expression is significantly decreased in pre-treatment diagnostic tumor biopsies from EAC patients with a poor response to neoadjuvant CRT (TRG 4 and 5), when compared to good responders (TRG 1 and 2) (n=18) [23]. Statistical analysis was performed using an unpaired, 2-tailed Student's t-test, *p < 0.05.