Table 1. Correlation of CHRDL2 expression with clinicopathologic features in CRC tissues.

Clinicopathologic features	Expression of CHRDL2 protein(IHC)
	Total cases	High expression	Low expression	P values
Age(years)				0.911
<60	76	38	38
≥60	49	24	25
Gender				0.792
Female	59	30	29
Male	66	32	34
Tumor diameter(cm)				0.009**
≤5	71	28	43
>5	54	34	20
Tumor location				0.858
Colon	69	35	34
Rectum	56	27	29
Depth of infiltration				0.385
Submucosa, musculeris propria	28	15	13
Subserosa	66	29	37
To the surrounding tissue	31	18	13
Histologic type				0.023*
Well differentiated	56	22	34
Morderately differentiated	49	25	24
Poorly differentiated	20	15	5
TNM staging				0.002**
I/II	81	32	49
III/IV	44	30	14
Lymph node metastasis				0.916
YES	45	26	19
NO	80	47	33

NOTE: p values were derived by using Chi-square test. (* p< 0.05. ** p< 0.01).