Table 2. Immunophenotypic characteristics of 33 cases with B-cell lymphoma involving Waldeyer's ring.
| Case no. | IHC | FISH | ||||||
|---|---|---|---|---|---|---|---|---|
| CD10 | BCL6 | MUM1 | Ki−67 | BCL2 | MYC | IGH/BCL2 | MYC | |
| 1−BL | ||||||||
| 1 | + | + | − | 95%+ | − | + | − | + |
| 2 | + | + | − | 90%+ | − | + | − | + |
| 3 | + | + | − | 100%+ | − | + | − | + |
| 4 | + | + | − | 95%+ | − | + | − | + |
| 5 | + | ND | ND | 95%+ | − | ND | ND | ND |
| 6 | + | − | − | 100%+ | − | + | − | + |
| 7 | + | + | − | 95%+ | − | ND | ND | ND |
| 2−DLBCL | ||||||||
| PDLBCL | ||||||||
| 8 | − | + | − | 60%+ | + | − | − | − |
| 9 | + | + | − | 80%+ | + | − | − | − |
| 10 | + | + | − | 90%+ | + | − | − | − |
| ADLBCL | ||||||||
| 11 | + | + | − | 80%+ | + | ND | − | − |
| 12 | − | + | + | 80%+ | + | − | ND | ND |
| 13 | − | + | − | 70%+ | + | + | − | − |
| 14 | − | − | + | 90%+ | + | ND | − | − |
| 15 | − | − | − | 70%+ | − | ND | ND | ND |
| 17 | − | + | + | 90%+ | + | ND | − | + |
| 16* | + | + | + | 90%+ | − | − | ND | − |
| 18 | − | + | + | 70%+ | + | ND | − | − |
| 19 | + | + | − | 70%+ | + | ND | ND | ND |
| 20 | − | ND | ND | 90%+ | ND | ND | ND | ND |
| 21 | − | + | + | 70%+ | + | ND | − | − |
| 22 | − | + | − | 70%+ | + | ND | ND | ND |
| 23 | − | + | − | 80%+ | + | − | − | − |
| 24 | − | + | − | 70%+ | + | ND | ND | ND |
| 25* | + | + | + | 80%+ | + | − | ND | ND |
| 26 | + | − | + | 60%+ | + | ND | ND | ND |
| 27 | + | − | + | 95%+ | − | − | − | − |
| 28 | − | + | + | 80%+ | + | − | − | − |
| 3− Follicular lymphoma | ||||||||
| PFL (MUM1 positive lymphoma) | ||||||||
| 29 | + | + | + | 70%+ | + | − | − | − |
| 30 | + | + | + | 50%+ | + | − | − | − |
| AFL / FL 3B | ||||||||
| 31 | + | + | − | 50%+ | + | ND | − | − |
| 32 | + | + | − | 95%+ | − | − | − | − |
| 4−MALT lymphoma | ||||||||
| 33 | − | − | − | 10%+ | + | ND | ND | ND |
*
In accordance to new classification “large B-cell lymphomas with IRF4 rearrangement”.
ADLBCL, adult diffuse large B-cell lymphoma; AFL, adult follicular lymphoma; BL, Burkitt lymphoma; DLBCL, diffuse large B-cell lymphoma; FL, follicular lymphoma; FISH, fluorescence in situ hybridization; IHC, immunohistochemistry; MALT, mucosa associated lymphoid tissue; ND, not done; PDLBCL, pediatric DLBCL; PFL, pediatric follicular lymphoma.